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Gastric cooling and menthol cause an increase in cardiac parasympathetic efferent activity in healthy adult human volunteers

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What is the central question of this study? How do gastric stretch and gastric cooling stimuli affect cardiac autonomic control? What is the main finding and its importance? Gastric stretch… Click to show full abstract

What is the central question of this study? How do gastric stretch and gastric cooling stimuli affect cardiac autonomic control? What is the main finding and its importance? Gastric stretch causes an increase in cardiac sympathetic activity. Stretch combined with cold stimulation result in an elimination of the sympathetic response to stretch and an increase in cardiac parasympathetic activity, in turn resulting in a reduction in heart rate. Gastric cold stimulation causes a shift in sympathovagal balance towards parasympathetic dominance. The coldā€induced bradycardia has the potential to decrease cardiac workload, which might be significant in individuals with cardiovascular pathologies.

Keywords: cardiac parasympathetic; stretch; increase cardiac; activity; gastric cooling

Journal Title: Experimental Physiology
Year Published: 2018

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