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Human amniotic membrane mesenchymal stem cell‐conditioned medium reduces inflammatory factors and fibrosis in ovalbumin‐induced asthma in mice

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What is the central question of this study? Is mesenchymal stem cell‐conditioned medium capable of improving the pathological alterations of ovalbumin‐induced asthma in mice? What is the main finding and… Click to show full abstract

What is the central question of this study? Is mesenchymal stem cell‐conditioned medium capable of improving the pathological alterations of ovalbumin‐induced asthma in mice? What is the main finding and its importance? Our study indicated that human amniotic membrane mesenchymal stem cell‐conditioned medium is capable of modulating inflammation, fibrosis, oxidative stress and the pathological consequences of ovalbumin‐induced allergic asthma in mice.

Keywords: stem cell; conditioned medium; cell conditioned; asthma mice; mesenchymal stem; ovalbumin induced

Journal Title: Experimental Physiology
Year Published: 2020

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