LAUSR

What is the central question of this study? Does short‐term heat acclimation enhance whole‐body evaporative heat loss and augment nitric oxide synthase (NOS)‐dependent cutaneous vasodilatation and NOS‐ and cyclooxygenase (COX)‐dependent sweating, in exercising older men? What is the main finding and its importance? Our preliminary data (n = 8) demonstrated that short‐term heat acclimation improved whole‐body evaporative heat loss, but it did not influence the effects of NOS and/or COX inhibition on cutaneous vasodilatation or sweating in older men during an exercise–heat stress. These outcomes might imply that although short‐term heat acclimation enhances heat dissipation in older men, it does not modulate NOS‐ and COX‐dependent control of cutaneous vasodilatation or sweating on the forearm.