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Angiotensin‐converting enzyme inhibitor prevents skeletal muscle fibrosis in diabetic mice

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What is the central question of this study? We questioned whether an angiotensin‐converting enzyme (ACE) inhibitor prevents skeletal muscle fibrosis in diabetic mice. What is the main finding and its… Click to show full abstract

What is the central question of this study? We questioned whether an angiotensin‐converting enzyme (ACE) inhibitor prevents skeletal muscle fibrosis in diabetic mice. What is the main finding and its importance? Administration of ACE inhibitor prevents the increase in skeletal muscle fibrosis during the early phase after induction of diabetes by streptozotocin. Our findings might provide a new therapeutic target for skeletal muscle abnormalities in diabetes.

Keywords: skeletal muscle; muscle; muscle fibrosis; inhibitor prevents

Journal Title: Experimental Physiology
Year Published: 2021

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