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What is the central question of this study? Is the frequency dependence of co‐transmitter release from postganglionic nerve fibres different for each transmitter? What is the main finding and its… Click to show full abstract
What is the central question of this study? Is the frequency dependence of co‐transmitter release from postganglionic nerve fibres different for each transmitter? What is the main finding and its importance? Release of co‐transmitters from the parasympathetic supply to detrusor smooth muscle can be independently regulated. This offers a targeted drug model to reduce selectively the release of transmitter associated with human pathologies (ATP) and may also be applicable to other smooth muscle‐based disorders of visceral tissues.
Journal Title: Experimental Physiology
Year Published: 2022
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