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The acute effect of a laboratory shame induction protocol on endothelial function in young, healthy adults

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What is the central question of this study? Shame is a form of social stress that involves internalizing social devaluations imposed by others. The aim of this study was to… Click to show full abstract

What is the central question of this study? Shame is a form of social stress that involves internalizing social devaluations imposed by others. The aim of this study was to determine, for the first time, how acutely experienced shame impacts endothelial function. What is the main finding and its importance? Brachial artery flow‐mediated dilatation, an index of endothelial function, was impaired after an intervention that acutely increased self‐reported shame. This occurred without increases in cortisol or tumor necrosis factor alpha receptor binding. Frequent or prolonged shame‐induced endothelial dysfunction could have important cardiovascular consequences.

Keywords: function; endothelial function; effect laboratory; acute effect; laboratory shame

Journal Title: Experimental Physiology
Year Published: 2022

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