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Energy metabolism and muscle activation heterogeneity explain V̇O2${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ slow component and muscle fatigue of cycling at different intensities

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What is the central question of this study? What are the physiological mechanisms underlying muscle fatigue and the increase in the O2 cost per unit of work during high‐intensity exercise?… Click to show full abstract

What is the central question of this study? What are the physiological mechanisms underlying muscle fatigue and the increase in the O2 cost per unit of work during high‐intensity exercise? What is the main finding and its importance? Muscle fatigue happens before, and does not explain, the V̇O2${\dot{V}}_{{{\rm{O}}}_{\rm{2}}}$ slow component ( V̇O2sc${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ ), but they share the same origin. Muscle activation heterogeneity is associated with muscle fatigue and V̇O2sc${\dot{V}}_{{{\rm{O}}}_{\rm{2}}{\rm{sc}}}$ . Knowing this may improve training prescriptions for healthy people leading to improved public health outcomes.

Keywords: muscle fatigue; explain dot; muscle; slow component; dot slow

Journal Title: Experimental Physiology
Year Published: 2023

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