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Changes in microvascular perfusion of heart and skeletal muscle in sheep around the time of birth

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What is the central question of this study? How does the microvascular perfusion of striated muscle change during the dynamic developmental period between the late gestation fetus and early neonate?… Click to show full abstract

What is the central question of this study? How does the microvascular perfusion of striated muscle change during the dynamic developmental period between the late gestation fetus and early neonate? What is the main finding and its importance? In both myocardium and skeletal muscle, perfusion of striated muscle is significantly reduced in the neonate compared to the late term fetus, but flow reserve is unchanged. The results suggest striated muscle capillary networks grow more slowly relative to the myofibres they nourish during the perinatal period.

Keywords: striated muscle; muscle; microvascular perfusion; perfusion; skeletal muscle; changes microvascular

Journal Title: Experimental Physiology
Year Published: 2022

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