A mixed domain method (MDM) is presented in this paper for modeling one-way linear/nonlinear wave propagation in biological tissue with arbitrary heterogeneities, in which sound speed, density, attenuation coefficients, and… Click to show full abstract
A mixed domain method (MDM) is presented in this paper for modeling one-way linear/nonlinear wave propagation in biological tissue with arbitrary heterogeneities, in which sound speed, density, attenuation coefficients, and nonlinear coefficients are all spatial varying functions. The MDM is based on solving a Westervelt-like equation. We validated the algorithm by studying a number of one-dimensional and two-dimensional problems. Overall, this study demonstrates that the MDM is a computationally efficient and accurate method when used to model wave propagation in biological tissue with relatively weak heterogeneities. We also proposed methods to improve the algorithm for moderately heterogeneous media.
               
Click one of the above tabs to view related content.