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Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

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Researchers show how the antidepressant drug fluoxetine targets a viral protein and inhibits viral replication. Click to show full abstract

Researchers show how the antidepressant drug fluoxetine targets a viral protein and inhibits viral replication.

Keywords: site enterovirus; targets allosteric; allosteric site; fluoxetine targets; aaa atpase; enterovirus aaa

Journal Title: Science Advances
Year Published: 2022

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