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Identifying and targeting the Achilles heel of a recalcitrant cancer

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Targeting replication stress response proteins in small cell lung cancer activates the innate immune cGAS-STING pathway leading to augmentation of immunotherapy’s antitumor response. Targeting replication stress response proteins in small… Click to show full abstract

Targeting replication stress response proteins in small cell lung cancer activates the innate immune cGAS-STING pathway leading to augmentation of immunotherapy’s antitumor response. Targeting replication stress response proteins in small cell lung cancer activates the innate immune cGAS-STING pathway leading to augmentation of immunotherapy’s antitumor response.

Keywords: response; heel recalcitrant; identifying targeting; cancer; achilles heel; targeting achilles

Journal Title: Science Translational Medicine
Year Published: 2021

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