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Combination cancer immunotherapies: Emerging treatment strategies adapted to the tumor microenvironment

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Immune checkpoint blockade (ICB) has revolutionized cancer treatment. However, resistance to ICB occurs frequently due to tumor-intrinsic alterations or extrinsic factors in the tumor microenvironment. This Viewpoint aims to give… Click to show full abstract

Immune checkpoint blockade (ICB) has revolutionized cancer treatment. However, resistance to ICB occurs frequently due to tumor-intrinsic alterations or extrinsic factors in the tumor microenvironment. This Viewpoint aims to give an update on recent developments in immunotherapy for solid tumors and highlights progress in translational research and clinical practice. Description Combination immunotherapy can help overcome resistance to immune checkpoint inhibitors.

Keywords: treatment; combination cancer; cancer; tumor microenvironment

Journal Title: Science Translational Medicine
Year Published: 2022

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