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The Brief Case: Tropheryma whipplei Infection Resulting in Neurological Symptoms

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PAS-D fi Neuro fi lament The patient was treated with 2 g ceftriaxone intravenously for 2 weeks, followed by 100 mg doxycycline twice daily and 200 mg hydroxychloroquine 3 times… Click to show full abstract

PAS-D fi Neuro fi lament The patient was treated with 2 g ceftriaxone intravenously for 2 weeks, followed by 100 mg doxycycline twice daily and 200 mg hydroxychloroquine 3 times per day for 1 year. Response to therapy is being evaluated by improvements in weight gain, insomnia, arthritis, and neurological symptoms. Initially, slight improvements were reported in insomnia, mental acuity, and mood. The patient was referred to physical therapy and speech therapy. As of this report, pro-gress in therapy has slowed, and the patient has again experienced confusion, falls, and worsening neurological symptoms similar to his presenting complaints.

Keywords: case tropheryma; neurological symptoms; whipplei infection; therapy; tropheryma whipplei; brief case

Journal Title: Journal of Clinical Microbiology
Year Published: 2022

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