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Is There a Breach in the Barrier Protecting Humans from Cervid Chronic Wasting Disease?

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Chronic wasting disease (CWD) is a prion-derived disease causing lethal spongiform encephalopathy in cervids like deer, elk, moose, and reindeer (1). It is similar to other zoonotic spongiform encephalopathies that… Click to show full abstract

Chronic wasting disease (CWD) is a prion-derived disease causing lethal spongiform encephalopathy in cervids like deer, elk, moose, and reindeer (1). It is similar to other zoonotic spongiform encephalopathies that are deadly to humans such as bovine spongiform encephalopathy, or mad cow disease, and holds potential for lethal spillover into human populations (2). Concern regarding potential spillover into humans is increasing as CWD is rapidly spreading across wild cervid populations in North America, cervids that are consumed by millions of hunters (3). In a recent mBio Opinion/Hypothesis piece, Osterholm …

Keywords: wasting disease; barrier protecting; protecting humans; chronic wasting; disease; breach barrier

Journal Title: mBio
Year Published: 2020

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