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mSphere of Influence: an Army Marching on Its Stomach—Malaria Parasites Sense and Subvert Host Nutrition

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Clare Harding works on the metal biology of the parasite Toxoplasma gondii. In this mSphere of Influence article, she reflects on how two papers from the laboratory of Maria Mota,… Click to show full abstract

Clare Harding works on the metal biology of the parasite Toxoplasma gondii. In this mSphere of Influence article, she reflects on how two papers from the laboratory of Maria Mota, “Host-mediated regulation of superinfection in malaria” by Portugal et al. (S). ABSTRACT Clare Harding works on the metal biology of the parasite Toxoplasma gondii. In this mSphere of Influence article, she reflects on how two papers from the laboratory of Maria Mota, “Host-mediated regulation of superinfection in malaria” by Portugal et al. (S. Portugal, C. Carret, M. Recker, A. E. Armitage, et al., Nat Med 17:732–737, 2011, https://doi.org/10.1038/nm.2368) and “Nutrient sensing modulates malaria parasite virulence” by Mancio-Silva et al. (L. Mancio-Silva, K. Slavic, M. T. Grilo Ruivo, A. R. Grosso, et al., Nature 547:213–216, 2017, https://doi.org/10.1038/nature23009), made an impact on her understanding of host-pathogen interactions by examining the complex interplay between parasites and their hosts’ nutritional status.

Keywords: influence army; biology; msphere influence; army marching; marching stomach; host

Journal Title: mSphere
Year Published: 2021

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