LAUSR

The high-risk clone ST167 associated with blaNDM-5 resistance determinant is currently recognized to be a source of public health concern worldwide (1–4), since it has been identified even beyond hospital borders, in companion animals, wastewater, rivers, and wildlife (5–8). In this work, we characterized an NDM-5-producing Escherichia coli ST167 collected in Italy from a liver sample of a 4-month-old cat who died from parvovirus hemorrhagic enteritis. The E. coli strain 167624 was tested for antibiotic susceptibility and sequenced using both Illumina and Nanopore technologies. Bacterial identification and antibiotic susceptibility tests were performed with the semiautomated system MicroScan autoSCAN4 (Beckman Coulter); results were interpreted according to EUCAST guidelines (v10.0-2020, http://www.eucast.org). The E. coli 167624 strain showed a multidrug-resistant (MDR) profile, being resistant to all the antibiotics tested, with the exception of colistin, amikacin, and fosfomycin (Table 1).