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Peptaibols as Potential Antifungal and Anticancer Antibiotics: Current and Foreseeable Development (Review)

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Today’s shortage of effective antimicrobial agents can be overcome by using antimicrobial peptides, which are produced naturally by a wide range of organisms, including microorganisms, plants, and mammals. Among these… Click to show full abstract

Today’s shortage of effective antimicrobial agents can be overcome by using antimicrobial peptides, which are produced naturally by a wide range of organisms, including microorganisms, plants, and mammals. Among these chemical groups, peptaibols are the well-known compounds with various biological activities, including antibacterial, antifungal, anticancer, antimycoplasmic, antitrypanosomal, and others. In this review, we summarize today’s knowledge on the sources, direct surface applications, and the mode of action of the peptaibols with anticancer and antifungal activity produced by filamentous fungi.

Keywords: peptaibols potential; antifungal anticancer; anticancer antibiotics; antibiotics current; anticancer; potential antifungal

Journal Title: Applied Biochemistry and Microbiology
Year Published: 2021

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