The possibility of obtaining vitamin K3 (2-methyl-1,4-naphthoquinone, menadione) by diene synthesis from accessible substrates such as 2-methylphenol (o-cresol) and 2-methylaniline (o-toluidine) was shown. The bifunctional catalysts of these processes are… Click to show full abstract
The possibility of obtaining vitamin K3 (2-methyl-1,4-naphthoquinone, menadione) by diene synthesis from accessible substrates such as 2-methylphenol (o-cresol) and 2-methylaniline (o-toluidine) was shown. The bifunctional catalysts of these processes are the aqueous solutions of Mo–V–P heteropoly acids, which allow the oxidation and diene synthesis to be performed as a one-pot process.
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