LAUSR

The influence of water–ethanol (H2O–EtOH), water–acetone (H2O–MeAc) and waterdimethylsulfoxide (H2O–DMSO) solvents on the reaction of the molecular complex formation between ether 18-crown-6 (18C6) and small peptide glycyl–glycyl–glycine (3Gly) has been studied at T = 298.15 K. The thermodynamic parameters for the reaction (log K, ΔrG, ΔrH, ΔrS) were obtained from calorimetric titration experiments carried out by means of the calorimetric system TAM III (TA Instruments, USA). The thermodynamics of the [3Gly18C6] molecular complex formation is discussed in comparison with thermodynamic parameters of complex formation between 18C6 and amino acids in mixed solvents using the sоlvation-thermodynamic approach.