"Design and development of macrocyclization methods for compounds with potential tuberculocidal activity to decrease CYP450 liver cytochrome inhibition"

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A procedure for macrocyclization of compounds with potential tuberculocidal activity was developed in order to obtaining compounds with a lower degree of inhibition of the key CYP 3A4 cytochrome. Click to show full abstract

A procedure for macrocyclization of compounds with potential tuberculocidal activity was developed in order to obtaining compounds with a lower degree of inhibition of the key CYP 3A4 cytochrome.

Keywords: tuberculocidal activity; potential tuberculocidal; compounds potential; macrocyclization

Journal Title: Russian Journal of General Chemistry
Year Published: 2017

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