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Thiosemicarbazides of diphenylphosphorylacetic acid and their cyclic derivatives have been synthesized. Functionalization of the obtained 1,2,4-triazole-3-thiones with ethyl 2-bromoacetate at the sulfur atom has been carried out, the obtained esters… Click to show full abstract
Thiosemicarbazides of diphenylphosphorylacetic acid and their cyclic derivatives have been synthesized. Functionalization of the obtained 1,2,4-triazole-3-thiones with ethyl 2-bromoacetate at the sulfur atom has been carried out, the obtained esters have been transformed into the corresponding hydrazides via hydrazinolysis. Preliminary pharmacological tests of the synthesized compounds have been performed.
Keywords:
hydrazide thiosemicarbazide;
diphenylphosphorylacetic hydrazide;
chemistry;
modification diphenylphosphorylacetic;
triazole units;
thiosemicarbazide triazole
Journal Title: Russian Journal of General Chemistry
Year Published: 2017
Link to full text (if available)
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Journal Title: Russian Journal of General Chemistry
Year Published: 2017
Link to full text (if available)
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recommendations!