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Catalytic Aminomethylation of Aminobenzamides with Bis(N,N-dimethylamino)methane and Carbamides

An effective method was developed for the synthesis of acyclic aniline derivatives bearing carbamide fragments by the reaction of carbamides with ortho-, meta-, and para-aminobenzamides and bis(N,N-dimethylamino) methane in the… Click to show full abstract

An effective method was developed for the synthesis of acyclic aniline derivatives bearing carbamide fragments by the reaction of carbamides with ortho-, meta-, and para-aminobenzamides and bis(N,N-dimethylamino) methane in the presence of NiCl2·6H2O and SmCl3·6H2O as catalysts.

Keywords: dimethylamino methane; catalytic aminomethylation; bis dimethylamino; aminobenzamides bis

Journal Title: Russian Journal of General Chemistry
Year Published: 2019

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