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Synthesis and Biological Activity of N-Aryl(alkyl)-2-[2-(9H-fluoren-9-ylidene)hydrazinylidene]-5,5-dimethyl-4-oxohexanamides

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Ring opening of 5-tert-butyl-3-[(9H-fluoren-9-ylidene)hydrazinylidene]furan-2(3H)-one by the action of primary amines afforded a series of new 2-[(9H-fluoren-9-ylidene)hydrazinylidene]-5,5-dimethyl-4-oxohexan-amides. The synthesized compounds were tested for antinociceptive and antimicrobial activities. Click to show full abstract

Ring opening of 5-tert-butyl-3-[(9H-fluoren-9-ylidene)hydrazinylidene]furan-2(3H)-one by the action of primary amines afforded a series of new 2-[(9H-fluoren-9-ylidene)hydrazinylidene]-5,5-dimethyl-4-oxohexan-amides. The synthesized compounds were tested for antinociceptive and antimicrobial activities.

Keywords: synthesis biological; biological activity; fluoren ylidene; ylidene hydrazinylidene; hydrazinylidene dimethyl

Journal Title: Russian Journal of General Chemistry
Year Published: 2019

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