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A series of new amide derivatives of imidazopyridine is synthesized and structures of the products are confirmed by 1H and 13C NMR, and mass spectral data. The synthesized derivatives are… Click to show full abstract
A series of new amide derivatives of imidazopyridine is synthesized and structures of the products are confirmed by 1H and 13C NMR, and mass spectral data. The synthesized derivatives are screened for their anticancer activity against four human cancer cell lines: lung cancer (A549), breast cancer (MCF-7), melanoma cancer (A375), and colon cancer (HT-29). Six synthesized compounds exhibit more potent activity than the control drug.
Keywords:
synthesis biological;
biological evaluation;
amide derivatives;
derivatives imidazopyridine;
cancer;
evaluation amide
Journal Title: Russian Journal of General Chemistry
Year Published: 2019
Link to full text (if available)
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Journal Title: Russian Journal of General Chemistry
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!