New pyrazole and pyridine derivatives have been synthesized from sulfanilamide and phenazone via diazotization and coupling with a wide range of α-CH acids followed by heterocyclization with hydrazine derivative, hydroxylamine… Click to show full abstract
New pyrazole and pyridine derivatives have been synthesized from sulfanilamide and phenazone via diazotization and coupling with a wide range of α-CH acids followed by heterocyclization with hydrazine derivative, hydroxylamine and cyanoacetamide. The antimicrobial tests of the products demonstrate high to moderate activity against Gram (−ve) bacteria and the tested fungi. No positive action of the products is observed against Gram (+ve) bacteria.
Keywords:
activity;
pyrazoles isoxazoles;
isoxazoles based;
sulfanilamide phenazone;
based sulfanilamide;
phenazone antimicrobial
Journal Title: Russian Journal of General Chemistry
Year Published: 2019
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Journal Title: Russian Journal of General Chemistry
Year Published: 2019
Link to full text (if available)
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recommendations!