Cyclization of 4-propargylsulfanylquinazoline under the action of iodine gave 3-iodomethyl[1,3]thiazolo[3,2-c]-quinazolinium triiodide, which is reduced with sodium iodide to form 3-methyl[1,3]thiazolo[3,2-c]quinazolinium iodide. The reaction with bromine in dichloromethane leads to the… Click to show full abstract
Cyclization of 4-propargylsulfanylquinazoline under the action of iodine gave 3-iodomethyl[1,3]thiazolo[3,2-c]-quinazolinium triiodide, which is reduced with sodium iodide to form 3-methyl[1,3]thiazolo[3,2-c]quinazolinium iodide. The reaction with bromine in dichloromethane leads to the formation of 3-bromomethyl[1,3]thiazolo-[3,2-c]quinazolinium bromide, and in acetic acid—2-(2-aminophenyl)-4-dibromomethyl-1,3-thiazole hydrobromide.
Journal Title: Russian Journal of General Chemistry
Year Published: 2020
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