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Immune response to Vi-antigen of Salmonella typhi is dependent on introduction of positive charge and shape of charged group into polysaccharide

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A model of a controlled conversion of polysaccharide Vi-antigen of S. typhi into zwitterionic antigen is proposed. The immunological properties of modifications of this antigen conjugated to a protein support… Click to show full abstract

A model of a controlled conversion of polysaccharide Vi-antigen of S. typhi into zwitterionic antigen is proposed. The immunological properties of modifications of this antigen conjugated to a protein support were studied.

Keywords: typhi; antigen salmonella; response antigen; antigen; immune response; salmonella typhi

Journal Title: Doklady Biochemistry and Biophysics
Year Published: 2017

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