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We found that the Su(Hw) insulator protein binds to all known Drosophila amplicons in follicular cells (DAFCs). Su(Hw) binding is required for ORC replication complex positioning on part of DAFCs… Click to show full abstract
We found that the Su(Hw) insulator protein binds to all known Drosophila amplicons in follicular cells (DAFCs). Su(Hw) binding is required for ORC replication complex positioning on part of DAFCs during early oogenesis. Our data allow us to expand the current view on the role of the Su(Hw) protein in Drosophila oogenesis as a transcription repressor. We assume that Su(Hw) is involved in the coordination of transcription and replication processes during oogenesis in Drosophila.
Keywords:
protein;
insulator protein;
oogenesis;
follicular cells;
amplicons follicular;
drosophila amplicons
Journal Title: Doklady Biochemistry and Biophysics
Year Published: 2018
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Journal Title: Doklady Biochemistry and Biophysics
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!