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Activation of Su(Hw)-Controlled Genes Is Associated with Increase in GAF Binding

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The interaction of the GAF protein with the promoters of neuron-specific genes during activation and repression of transcription was studied. We showed that, while the Su(Hw) protein remains stably associated… Click to show full abstract

The interaction of the GAF protein with the promoters of neuron-specific genes during activation and repression of transcription was studied. We showed that, while the Su(Hw) protein remains stably associated with the promoters of these genes at different transcriptional state, the GAF protein level is significantly higher when transcription is activated.

Keywords: activation; activation controlled; gaf; associated increase; genes associated; controlled genes

Journal Title: Doklady Biochemistry and Biophysics
Year Published: 2019

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