LAUSR

Background The ILAR criteria require the presence of arthritis to classify a patient as having sJIA. The sJIA patients prior to the onset of arthritis (suspected sJIA) appeared clinically similar to patients fulfilling the ILAR criteria for sJIA. Objectives Children with sJIA may have a delayed onset of arthritis and it fail to fulfill the ILAR criteria for sJIA. This study was undertaken to determine whether the Yamaguchi criteria is useful in classification of child with sJIA particularly in pre-arthritic phase of illness. Methods Retrospective chart review all patients with a diagnosis of sJIA in Hallym University Medical Center from Feb. 2002 through April 2016. Results Total 73 patients were diagnosed by ILAR classification criteria. 38 boys and 35 girls formed the study cohort. There are only 20 patients who are fulfilled of ILAR criteria in sJIA. Characteristics sJIA (n=20) suspected (n=53) Total (n=73) Evanescent Rash 19 24 Sore throat 1 5 Lymphadenopathy 2 11 Hepatomegaly 1 11 Splenomegaly 4 10 37 patients were diagnosed with suspected sJIA due to have not an arthritis. 36 patients were presented the arthritis at the onset of sJIA. The Yamaguchi criteria was fulfilled in a higher number of patients in the study (n=44) as compared to the ILAR criteria (n=20). Among the patients with the absence of arthritis (n=37), 25 patients fulfilled the Yamaguchi criteria. (67.5%). ILAR criteria Yamaguchi criteria Yamaguchi criteria fulfilled 16 28 Yamaguchi critieria not fulfilled 4 25 Total cohort 20 53 Conclusion Overall the Yamaguchi criteria was fulfilled in a higher number of patients in the study (60.2%) as compared to the ILAR criteria (27.3%). The failure of ILAR criteria was mainly due to the absence of arthritis. The Yamaguchi criteria is more helpful to diagnosis of sJIA. The Yamaguchi criteria may be useful on early diagnosis and treatment for patient with delayed onset arthritis at onset of disease. Reference [1] Kumar S., Junhiraman D.S. and Jajam L. et al: Application of the Yamaguchi criteria for classification of “suspected” systemic juvenile idiopathic arthritis (sJIA). Pediatric Rheumatology 2012, 10:40. Disclosure of Interests None declared