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Response to: ‘Off-label use of tofacitinib: a potential treatment option for SAPHO syndrome’ by Xie et al

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We would like to thank Xie et al 1 for their interest in our paper2 and for their insights into the possible mechanism of action of tofacitinib in synovitis, acne,… Click to show full abstract

We would like to thank Xie et al 1 for their interest in our paper2 and for their insights into the possible mechanism of action of tofacitinib in synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome and the trend of stratified medicine. As Xie et al highlighted, tofacitinib presented clinical and radiological efficacy in patients with SAPHO syndrome who had an inadequate response to tumour necrosis factor (TNF) inhibitors or bisphophonates. Similarly, a clinical trial proved that …

Keywords: xie; sapho syndrome; use tofacitinib; label use; response label

Journal Title: Annals of the Rheumatic Diseases
Year Published: 2020

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