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Correspondence on 'Increased risk of systemic lupus erythematosus in patients with autoimmune haemolytic anaemia: a nationwide population-based cohort study'.

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We read with great interest a letter by Mo et al 1 pointing out that patients with autoimmune haemolytic anaemia (AIHA) had a significantly higher risk of systemic lupus erythematosus… Click to show full abstract

We read with great interest a letter by Mo et al 1 pointing out that patients with autoimmune haemolytic anaemia (AIHA) had a significantly higher risk of systemic lupus erythematosus (SLE) than non-AIHA individuals. Considering that AIHA is clearly over-represented in patients with SLE, often occurring before the diagnosis of SLE, the authors nicely investigated the association between AIHA and SLE incidence in a nationwide, population-based, matched cohort study and demonstrated a high association (HR=54.7) between AIHA and SLE risk.1 SLE is a chronic, highly heterogeneous autoimmune disease, characterised by differences in autoantibody profile, serum cytokines and a multisystem involvement.2 AIHA is a highly heterogeneous pathological condition caused by the increased destruction of …

Keywords: risk; risk systemic; systemic lupus; autoimmune haemolytic; patients autoimmune; haemolytic anaemia

Journal Title: Annals of the rheumatic diseases
Year Published: 2020

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