LAUSR

power plan had been implemented, showed that 51% of IV maintenance fluids were isotonic. This increased to 88%, after the power plan was introduced. Across both the second and third audit periods, there were 2 infants who developed hyponatraemia after receiving maintenance IV fluids. One was on a mixture of TPN and isotonic fluid, the other was on hypotonic fluids. There was only one incident of hypernatraemia (146), which occurred while on 10% dextrose infusion. Conclusion The prescription of isotonic solutions has increased significantly since the EPR power plan for paediatric fluid prescriptions was introduced. This had a much greater impact than trying to encourage guideline adherence alone. There is little published evidence on the safety of isotonic fluids in young infants. We have not observed any significant hypernatraemia since the increase in isotonic fluid usage.