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How to use autoantibodies in suspected paediatric rheumatic disease

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Autoantibodies can be an important indicator of paediatric rheumatic disease and useful in establishing a diagnosis. However, autoantibodies may be requested in cases where the patient does not have clinical… Click to show full abstract

Autoantibodies can be an important indicator of paediatric rheumatic disease and useful in establishing a diagnosis. However, autoantibodies may be requested in cases where the patient does not have clinical features strongly suggestive of a rheumatic disease. This can lead to further unnecessary investigations, specialist referral and undue anxiety for the family. The aim of this article is to provide guidance for when it is appropriate to request autoantibodies, which ones to perform and how to interpret the results.

Keywords: suspected paediatric; autoantibodies suspected; disease; rheumatic disease; paediatric rheumatic; use autoantibodies

Journal Title: Archives of Disease in Childhood
Year Published: 2022

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