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Intraventricular haemorrhage and obstructive hydrocephalus in a term neonate: an uncommon presentation of haemophilia B

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A 12-day-old boy, first born to a non-consanguineous Indian couple, presented with a history of antenatally diagnosed hydrocephalus during ultrasound at 32 weeks. Antenatal period was uneventful, and the child was… Click to show full abstract

A 12-day-old boy, first born to a non-consanguineous Indian couple, presented with a history of antenatally diagnosed hydrocephalus during ultrasound at 32 weeks. Antenatal period was uneventful, and the child was born at 37 weeks (early term) by spontaneous normal vaginal delivery with Apgar scores of 8 and 9. His weight and head circumference at birth were 2.4 kg and 33 cm, respectively. There was no family history of bleeding disorders or maternal intake of anticoagulants, and the baby had received vitamin K injection at birth. No genetic test or amniotic fluid analysis was performed antenatally. Examination revealed a well-thriving child with no evidence of liver disease, rash, skin bleeds or encephalopathy. The anterior fontanelle was tense, with normal neurological examination. Postnatal ultrasonography (USG) of the cranium at 6 hours of life revealed dilated ventricles with …

Keywords: haemorrhage obstructive; hydrocephalus term; term; intraventricular haemorrhage; term neonate; obstructive hydrocephalus

Journal Title: BMJ Case Reports
Year Published: 2018

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