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Leucocyte adhesion defect presenting as fulminant sepsis in a new born

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We present a term neonate with severe sepsis, presenting on day 10 of life. The neonate presented with bilateral purulent eye discharge and hepatosplenomegaly. On investigation, persistent leucocytosis was observed… Click to show full abstract

We present a term neonate with severe sepsis, presenting on day 10 of life. The neonate presented with bilateral purulent eye discharge and hepatosplenomegaly. On investigation, persistent leucocytosis was observed and thus the possibility of leucocyte adhesion defect was considered. Flow cytometry confirmed the diagnosis.

Keywords: leucocyte adhesion; adhesion defect; defect presenting; sepsis

Journal Title: BMJ Case Reports
Year Published: 2019

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