LAUSR

© BMJ Publishing Group Limited 2021. No commercial reuse. See rights and permissions. Published by BMJ. DESCRIPTION A 45yearold man, with poorly controlled diabetes (HbA1c10.1), presented with fever and gluteal pain for 3 days. On examination, there was a swelling over left gluteal region with induration and an overlying discharging sinus. Ultrasonography of the swelling showed subcutaneous oedema with underlying collection. Incision and drainage was done and the pus was sent for bacteriological, tubercular, fungal stains and culture. Gram stain showed gram positive cocci in clusters and subsequently there was growth of methicillinresistant Staphylococcus aureus, for which the patient was started on linezolid. Two days later, the patient developed newonset cough with shortness of breath. A chest radiograph was done which showed bilateral nodular densities with cavitation (figure 1). Subsequently, a highresolution CT of chest showed multiple cavitating nodules along with feeding vessel sign and bilateral pleural effusion (figure 2). There was no any evidence of peripheral thrombophlebitis. A twodimensional transthoracic echocardiography was also done, which did not show any evidence of infective endocarditis. With the given radiological picture, a differentials of septic pulmonary emboli (SPE), pulmonary vasculitis, pulmonary infections(tubercular or fungal) and metastatic lesions were kept. Potassium hydroxide (KOH) stain and fungal cultures from respiratory samples were negative. Sputum sent for acidfast bacilli and GeneXpert was also negative. There was no associated cervical, mediastinal lymphadenopathy or discernible mass. The clinical picture and duration of illness was not suggestive of pulmonary vasculitis and antineutrophilic cytoplasmic antibody was also negative. With the given clinical scenario and imaging findings a final diagnosis of gluteal abscess with SPE was made and the patient was managed with intravenous antibiotics for 4 weeks to which the patient showed steady improvement. SPE are caused by embolisation of thrombi containing microorganisms to pulmonary vascular beds causing infarctions and microabscesses. Common causes of SPE include infective endocarditis, skin and softtissues infection, intravascular catheters, pacemakers, intravenous drug use, dental abscess, septic thrombophlebitis, puerperal sepsis, etc. The characteristic radiological finding on CT scan is bilateral discrete nodules with varying degrees of cavitation; the nodules may differ in size reflecting recurrent embolic showers. Other findings include subpleural wedgeshaped opacities and feeding vessel sign (a distinct vessel leading directly to a nodule), which is considered to be pathognomic of SPE. Pleural effusion or empyema may occasionally complicate SPE. Radiological features of SPE can mimic other conditions like pulmonary vasculitis (granulomatosis with polyangiitis), extrathoracic metastasis (commonly squamous cell carcinoma) and pulmonary thromboembolism. 9 The duration as well as clinical manifestations serves as