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Delayed drug hypersensitivity reaction to secukinumab in a patient with hidradenitis suppurativa

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A woman in her 30s presented to the dermatology clinic with widespread, pruritic, red papules and plaques involving the ears, trunk and extremities. The rash developed a few days after… Click to show full abstract

A woman in her 30s presented to the dermatology clinic with widespread, pruritic, red papules and plaques involving the ears, trunk and extremities. The rash developed a few days after receiving her second injection of secukinumab, which was initiated for recalcitrant Hurley stage III hidradenitis suppurativa. Investigations revealed a psoriasiform drug hypersensitivity reaction secondary to secukinumab. In this report, we describe the clinical course, histopathological correlation and treatment of this rarely documented reaction.

Keywords: reaction; hidradenitis suppurativa; drug hypersensitivity; hypersensitivity reaction

Journal Title: BMJ Case Reports
Year Published: 2022

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