We welcome the application of rigorous standards to preclinical research, but the position expressed by Ritskes-Hoitinga and Wever misses the central value of most animal experimentation.1 Medical research exists on… Click to show full abstract
We welcome the application of rigorous standards to preclinical research, but the position expressed by Ritskes-Hoitinga and Wever misses the central value of most animal experimentation.1 Medical research exists on a spectrum from fundamental discovery to clinical validation. Human studies must meet very high levels of proof and, therefore, can generally rigorously test only a single hypothesis. The vast majority …
               
Click one of the above tabs to view related content.