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Neoaortic growth rate and diameter as risk factors for neoaortic valve regurgitation after arterial switch operation

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To the Editor In our recently published article,1 neoaortic dimensions and neoaortic valve function derived from echocardiographic imaging were longitudinally assessed from birth until adulthood in 345 patients after arterial… Click to show full abstract

To the Editor In our recently published article,1 neoaortic dimensions and neoaortic valve function derived from echocardiographic imaging were longitudinally assessed from birth until adulthood in 345 patients after arterial switch operation for transposition of the great arteries. From these data, neoaortic root dimensions were independently associated with the development of at least moderate neoaortic valve regurgitation (AR≥moderate) by time-dependent Cox-regression (TD-Cox) analysis. With this analysis, no significant association could be established for the development of AR≥mild, and no relationship between neoaortic annulus dimensions and AR of any severity could be determined. Recent developments in biostatistics allow …

Keywords: arterial switch; neoaortic valve; valve regurgitation; switch operation

Journal Title: Heart
Year Published: 2020

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