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What is unusual or unique about this transrectal ultrasound-guided left midzone prostatic biopsy in a 66-year-old Asian Indian with a raised serum prostate-specific antigen (1278 ng/mL)? Review the high quality, interactive… Click to show full abstract
What is unusual or unique about this transrectal ultrasound-guided left midzone prostatic biopsy in a 66-year-old Asian Indian with a raised serum prostate-specific antigen (1278 ng/mL)? Review the high quality, interactive digital Aperio slide at http://virtualacp.com/JCPCases/jclinpath-2020-206537/ and consider your diagnosis. 1. The spaces are an artefact of fixation. 2. The spaces represent an artefact of sectioning. 3. The spaces represent extraprostatic fat infiltration by prostatic adenocarcinoma. 4. Intraprostatic adipose tissue involved by adenocarcinoma. The correct answer is after the discussion. Until fairly recently, it was believed that there was no intraprostatic fat. Thus, a comment that there was infiltration of fat by a prostatic carcinoma implied that it was extraprostatic fat and hence, a pT3 disease. Invasion of fat by …
Journal Title: Journal of Clinical Pathology
Year Published: 2020
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