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The spectrum of diseases of optic neuromyelitis corresponds to a set of rare inflammatory and autoimmune diseases of the central nervous system (CNS), with consequent demyelination of CNS neurons that… Click to show full abstract
The spectrum of diseases of optic neuromyelitis corresponds to a set of rare inflammatory and autoimmune diseases of the central nervous system (CNS), with consequent demyelination of CNS neurons that predominantly affects the spinal cord, optic nerve and brainstem causing respiratory insufficiency in 6.3% of cases. Neuromyelitis optica (NMO) was until recently considered a variant of multiple sclerosis (MS). Its aetiopathogenesis remains unknown, but recent advances describe an association with an autoimmunity production of IgG against the aquoporin-4 …
Journal Title: Postgraduate Medical Journal
Year Published: 2020
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