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This study shows that in contrast to the rat, mouse ventricular Na+/Ca2+ exchange current density is lower in the t-tubules than in the surface sarcolemma and Ca2+ current is predominantly… Click to show full abstract
This study shows that in contrast to the rat, mouse ventricular Na+/Ca2+ exchange current density is lower in the t-tubules than in the surface sarcolemma and Ca2+ current is predominantly located in the t-tubules. As a consequence, the t-tubules play a role in recovery (autoregulation) from reduced, but not increased, sarcoplasmic reticulum Ca2+ release.
Keywords:
autoregulation;
mouse ventricular;
sarcolemmal distribution;
physiology;
ca2;
distribution ica
Journal Title: American Journal of Physiology - Heart and Circulatory Physiology
Year Published: 2017
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Journal Title: American Journal of Physiology - Heart and Circulatory Physiology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!