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Mechanisms for the Resolution of Organ Fibrosis.

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Fibrosis is a dynamic process with the potential for reversibility and restoration of near-normal tissue architecture and organ function. Herein, we review mechanisms for resolution of organ fibrosis, in particular… Click to show full abstract

Fibrosis is a dynamic process with the potential for reversibility and restoration of near-normal tissue architecture and organ function. Herein, we review mechanisms for resolution of organ fibrosis, in particular that involving the lung, with an emphasis on the critical roles of myofibroblast apoptosis and clearance of deposited matrix.

Keywords: fibrosis; physiology; mechanisms resolution; resolution organ; organ fibrosis

Journal Title: Physiology
Year Published: 2019

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