LAUSR

Introduction We first examined the association of an ocular refractive error with allergic conjunctivitis in school children and then examined this association in children attending a suburban school and an urban school. Methods We enrolled 426 children attending a primary school in a suburban area and 550 children attending a primary school in an urban area which had a higher level of air pollution. Allergic conjunctivitis was defined as the diagnosis of this condition at any time during a child's life. The ophthalmic examinations included measurements of visual acuity and refraction, and a slit lamp examination. Skin prick tests were also performed at each school during 2018. The significance of associations was determined by the calculation of odds ratios (ORs) and 95% confidence intervals (CIs). Results Astigmatism (increase of 1 cylindrical diopter) was associated with allergic conjunctivitis in children overall (OR = 1.287, 95% CI = 1.010 to 1.642) and in children attending the urban school (OR = 1.408, 95% CI = 1.029 to 1.926), but not in children attending the suburban school (OR = 1.040, 95% CI = 0.672 to 1.610). Allergic conjunctivitis also had a higher prevalence among children attending the urban school. The urban school had higher levels of air pollutants than the suburban school. Skin prick tests indicated that the major allergens in children with allergic conjunctivitis were house dust mites and various types of pollen. Conclusion Astigmatism is associated with allergic conjunctivitis in children attending an urban school.