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Synthesis of Phenols via Metal-Free Hydroxylation of Aryl Boronic Acids with Aqueous TBHP

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An alternate procedure for oxidative hydroxylation of aryl boronic acids with aqueous TBHP to access phenols is described. The protocol tolerated various functional groups substituted with aromatic rings. The reaction… Click to show full abstract

An alternate procedure for oxidative hydroxylation of aryl boronic acids with aqueous TBHP to access phenols is described. The protocol tolerated various functional groups substituted with aromatic rings. The reaction was performed in water and free from transition metal oxidants.

Keywords: boronic acids; hydroxylation aryl; aqueous tbhp; aryl boronic; acids aqueous

Journal Title: Journal of Chemistry
Year Published: 2020

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