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BRCA2 Germline Mutations Identify Gastric Cancers Responsive to PARP Inhibitors

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PARP inhibition is a potential strategy for treating patients with gastric cancer with mutated BRCA2 or homologous repair deficiency, including patients with familial intestinal gastric cancer, for whom BRCA2 germline… Click to show full abstract

PARP inhibition is a potential strategy for treating patients with gastric cancer with mutated BRCA2 or homologous repair deficiency, including patients with familial intestinal gastric cancer, for whom BRCA2 germline testing should be recommended.

Keywords: brca2 germline; mutations identify; germline mutations; gastric cancers; cancers responsive; identify gastric

Journal Title: Cancer Research
Year Published: 2023

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