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Systemic IL12 therapy has potent antitumor effects, but clinical delivery of this potent cytokine has been complicated by systemic toxicity. A novel strategy to deliver IL12 to the tumor microenvironment… Click to show full abstract
Systemic IL12 therapy has potent antitumor effects, but clinical delivery of this potent cytokine has been complicated by systemic toxicity. A novel strategy to deliver IL12 to the tumor microenvironment appears promising in a first-in-human study, appearing to stimulate tumor-specific adaptive immune responses with minimal systemic toxicity. See related article by Strauss et al., p. 99
Keywords:
il12;
delivery;
place il12;
right time;
time place;
therapy
Journal Title: Clinical Cancer Research
Year Published: 2018
Link to full text (if available)
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Journal Title: Clinical Cancer Research
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!