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Model Informed Drug Development: Novel Oncology Agents are Lost in Translation

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Excitement around and investment in oncology drug development are at unprecedented levels. To maximize the health impact and productivity of this research and development investment, quantitative modeling should impact key… Click to show full abstract

Excitement around and investment in oncology drug development are at unprecedented levels. To maximize the health impact and productivity of this research and development investment, quantitative modeling should impact key decisions in early clinical oncology including Go/No-Go decisions based on early clinical data, and dose selection for late stage studies. See related article by Bottino et al., p. 6633

Keywords: informed drug; development; drug development; oncology; model informed

Journal Title: Clinical Cancer Research
Year Published: 2019

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