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A New Pathway Emerges to Interpret Lung Cancer Genomic Alterations

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The clinical utility of performing tumor genetic testing to assess for alterations beyond the known targetable oncogenes in lung adenocarcinoma is unclear. Analyzing cancer pathway alterations beyond single oncogenic driver… Click to show full abstract

The clinical utility of performing tumor genetic testing to assess for alterations beyond the known targetable oncogenes in lung adenocarcinoma is unclear. Analyzing cancer pathway alterations beyond single oncogenic driver mutations in addition to markers of tumor mutation burden and genomic instability may provide additional predictive and prognostic information. See related article by Zhou et al., p. 7475

Keywords: pathway emerges; lung; cancer; emerges interpret; new pathway

Journal Title: Clinical Cancer Research
Year Published: 2019

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